Facebook's social network has more than 2 billion users.
In response, Facebook trotted out its own op-ed in the New York Times on Saturday, this time written by former deputy minister of the United Kingdom and current Facebook vice president for global affairs and communications Nick Clegg. The company has more than 6 billion monthly active users across its platforms, which also include WhatsApp and Instagram.
He accused Facebook of acquiring or copying all of its competitors to achieve dominance in the social media field, meaning that investors were reluctant to back any rivals because they know they can not compete for long.
While Facebook is a large company, it consists of "many smaller pieces" that fight for customers.
Hughes is confident that accountability can come through government intervention, despite a perception that lawmakers are clueless about things like social media following Zuckerberg's testimony on Capitol Hill.
"I think he's taking those responsibilities seriously", Buttigieg said, referring to Zuckerberg, describing him as "somebody who cares about what his product is doing for and to the country and the world".
He comes to the conclusion that Uncle Sam should step in and break them up, which is of course a Paul Krugman-type of absurd, socialistic demand that would punish shareholders and destroy America's greatest job creator - Silicon Valley (as well as Manhattan's own Silicon Alley).
Critics say the company's pivot to privacy, which will introduce more encrypted communications, will restrict Facebook's ability to police propaganda, hate speech and another abusive behaviour.
"I think a lot of people here in the tech sector still have a David mentality when they've increasingly turned into Goliath", he said.
The Facebook op-ed also accused Hughes and other critics of misunderstanding the goal of federal antitrust law.
The company has been rocked by a series of scandals recently, including allowing its users' data to be harvested by research companies and its slow response to Russian Federation using Facebook as a means to spread disinformation during the 2016 U.S. election campaign.
Zuckerberg in March wrote on op-ed in which he called for regulators to play a "more active role" in establishing rules for the internet. Hughes implied social media sites are just as essential to Americans as smart phones, but unlike that market, Facebook doesn't have enough competition.
Senator Elizabeth Warren, who is seeking the Democratic nomination for the 2020 presidential election, has vowed here to break up Facebook, Amazon.com Inc and Alphabet Inc's Google if elected.
"The way forward is to heavily scrutinize future mergers and to ensure no company has anti-competitive platform privileges", Khanna said. After the Cambridge Analytica scandal, Hughes said he started to speak up and had some exchanges with Zuckerberg about the issues.