Blake was angry at having to wait for two medal ceremonies to take place before the race.
Mayer won with 8,768 points. Ukraine's Yuliia Levchenko took silver in 2.01 and Poland's Kamila Licwinko was third in 1.99. Named a World Athlete of the Year and Track & Field Athlete of the Year in seasons past, he holds a trio of Olympic titles in the 200-meter event.
Only the javelin and the 1,500 meters remain in the competition. "It's a sensational feeling to become world champions on home turf".
The Jamaican star and eight-time Olympic champion competed as part of his country's 4x100m relay team at the London 2017 IAAF World Championships.
The women came second in their heat with a season's best time of 3:24.74, behind the United States. They beat Jamaican by 0.07s.
Nathaneel Mitchell-Blake of Great Britain edged Christian Coleman down the stretch to run the fastest time in the world this year in the event at 37.47 seconds, a new British record.
It was less convincing, however, for the men's four, who progressed as fastest qualifiers into the final.
Instead Bolt ended up flat on the track, pulling up with that appeared to be a hamstring injury about halfway down the anchor leg.
Bowie, who won the 100 meters this week, ran a strong anchor leg, leaving behind the opposition to finish in 41.82 seconds.
France and China also qualified.
Britain, who came fifth in the Olympics a year ago, had looked in good form when qualifying but they were not expected to challenge Jamaica and the USA. They also advanced to the final.
Completing the final lineup were the Netherlands, featuring twice 200m champion Dafne Schippers, and 2015 bronze medallists Trinidad and Tobago.
"To run it with Danny Talbot after such disappointment in London 2012, it is so special to come back", said Gemili, who was not selected for the individual races and missed an Olympic 200m bronze by three thousandths of a second a year ago.
Mayer is the first Frenchman to win the title.
Saturday marks the end of the Usain Bolt's career.
Team GB's first ever Men's 4x100m World Championship success followed the silver medal won by Team GB Women.
Bolt had just received the baton from Yohan Blake with Jamaica in contention for a medal.
Few things can compare to the phenomenon of watching Bolt make futile the efforts of the other runners.