The English actor, 51, is said to have hurt himself whilst filming the upcoming movie - now dubbed Bond 25 - in Jamaica.
According to an unnamed source for The Sun, Craig "was sprinting during filming when he slipped and fell quite awkwardly".
The insider added: "He was in quite a lot of pain and was complaining about his ankle". He was also pretty angry that it had happened. He threw his suit jacket on the ground in sheer frustration'.
According to British newspaper The Sun (via Variety), star Daniel Craig sustained an injury while sprinting on the Jamaican set of the spy thriller, thus prompting production to be paused while he was flown to the US for X-rays.
It's no wonder that Craig is eager to hang up the gun and suit - the poor actor has endured all manner of injury ever since he took on the mantle of Agent 007, getting two teeth knocked out during his first stunt scene in Casino Royale, slicing off a fingertip and tearing a shoulder muscle in Quantum of Solace, and injuring his knee during a fight scene in 2015's Spectre.
Bond 25 has experienced a lot of behind-the-scenes drama already.
Cary Joji Fukunaga is directing from a script by Neal Purvis, Robert Wade, Scott Z. Burns and Phoebe Waller-Bridge.
Bond 25, which does not yet have a title, is now slated for release on April 8, 2020.
The cast, led by Craig, Naomie Harris, Lea Seydoux, Lashana Lynch and Ana de Armas, have been on location in Jamaica but are heading back to Europe to link up with Rami Malek, Ralph Fiennes and Ben Whishaw. The official log-line states that Bond's "peace is short-lived when his old friend Felix Leiter [Wright] from the Central Intelligence Agency turns up asking for help".