It was also a display of muscle-flexing by City, Liverpool and Spurs that will have been noted by the likes of Barcelona and Juventus, the two continental heavyweights most likely to stand in the way of an English triumph in the final in Madrid on June 1.
United and City will discover the identity of their quarter-final opponents when the draw for the last eight is made in Nyon on Friday morning.
"They would all need a period to psychologically switch off and we'd have to look at Champions League final players when we got to it".
Liverpool can return to the top of the Premier League with a win at Fulham on Saturday.
Former Blaugrana coach Pep Guardiola's team are one of the favourites to win the title and Manchester City have the quality between the four lines, as well as on the bench, to reach the Estadio Wanda Metropolitano final.
What's more, the report states that Barcelona players want to avoid Manchester City and Juventus. He helped Real win four of the past five Champions Leagues and it is hard to imagine the Spanish giants winning any of them without the Portuguese star's contribution.
The last time the two teams faced each other was in the 2011 UEFA Supercup, when Barcelona won 2-0.
Liverpool's run to the final previous year signalled a re-awakening and this season, with holders Real Madrid, Bayern and PSG all out, the odds are shortening on the first all-English final since United beat Chelsea on penalties in Moscow in 2008. Ronaldo's never even been on the losing side against English opposition in the knock-out stages of the Champions League even dating back to his time at United, when Sir Alex Ferguson's men overcame the likes of Chelsea and Arsenal in all-English encounters.
"Every team left in the competition is a good side", said Milner.
Both Manchester clubs progressed to the last eight of the competition, but UEFA regulations do not allow two teams in the same city to play on the same day, nor on consecutive nights.
This means that the chances are there will be at least one all English match during the next round of games in Europe's elite competition, as half of the teams remaining are from the Premier League.