The actress is accused of making a $15,000 donation to get involved in a college entrance exam cheating scheme on behalf of their oldest daughter, who reportedly took the SATs in December 2017 and received a 1420, which was a 400 point improvement over her PSAT score.
Prosecutors allege that fake athletic profiles were also created to make students look like strong high school athletes when they actually weren't.
John Vandemoor, a former Stanford University sailing coach who worked with Singer, also pleaded guilty to racketeering conspiracy. In a conversation last June with a cooperating witness, he was told his daughter needed to "be stupid" when a psychologist evaluated her for learning disabilities that would entitle her to more time to take the test, according to court papers.
The actress was also granted a signature bond of $250,000. He's accused of spearheading the scam, including allegedly facilitating cheating on college entrance exams like the SAT and ACT, Photoshopping prospects' heads on athletes' bodies, and bribing admissions officers.
Prosecutors say the coaches were bribed to indicate students were being considered as athletic recruits, because universities "typically apply different criteria when evaluating applications from students with demonstrated athletic abilities".
Ms Huffman and Ms Loughlin were due to appear in Federal Court in Los Angeles later on Tuesday, prosecutors said.
According to CNN, Macy is not charged or named in court documents.
Officials said initial court appearances are planned later on Tuesday. She became a star on "Full House", a standout hit of ABC's family-friendly TGIF lineup in the early 1990s, and appeared on the recent Netflix reboot "Fuller House". The couple allegedly agreed to pay bribes totaling $500,000 to have their daughters designated as recruits for the USC crew team, even though they did not participate in crew.
Federal prosecutors in Boston charged William "Rick" Singer, 58, with running the scheme through his Edge College & Career Network, which charged up to $2.5 million per child for the services, which were masked as contributions to a scam charity. In an open letter, Mamet said: "That a parent's zeal for her children's future may have overcome her better judgment for a moment is not only unfortunate, it is, I know we parents would agree, a universal phenomenon".
It has been claimed the IRS (Internal Revenue Service) and the Federal Bureau of Investigation have set out to arrest 46 individuals across the United States of America, after uncovering a $25 million ($35 million AUD) fraud scheme which includes allegedly faking test scores.
Messages seeking comment from Huffman's representatives were not immediately returned.
None of the universities or the companies who run the tests were implicated, and none of the students involved were charged.
Indeed, Loughlin's daughter, Olivia Giannulli, made headlines a year ago when she bragged on YouTube that she was going to college to party and likely would not have much time for classes.