Forecasters say arctic cold will follow the snow.
In all likelihood, this week will deliver the coldest temperatures and highest wind chill values of the winter.
The snow is forecast to come ahead of a cold front moving through Tuesday night.
While Winnipeg, southern Manitoba - well, really the entire province - has been dealing with significant cold weather lately, the daily mean temperature as of January 28 is still slightly above normal. Minnesota temperatures could hit minus 30 degrees with a wind chill of negative 60.
Outside of Chicago, in the Midwest, temperatures are forecast to plummet. The western parts of Minnesota and IL, as well as North and South Dakota, are under wind chill warnings, the NWS also reported.
Highs will climb into the 30s and 40s in the Midwest on Saturday, with some places nearing 50 degrees.
In Des Moines, where the wind chill may dip to minus-40 on Wednesday, the National Weather Service advised home and business owners to make sure they were ready for the impending cold snap.
There's no arguing the Minneapolis-St.
Cook, Kane, DuPage, Will, Grundy, LaSalle and Kendall counties will remain under a winter weather advisory from 9 p.m. Sunday until 6 p.m. Monday, the weather service said. "There's no sugarcoating it, the weather will get extremely cold", it tweeted.
Clarification: The headline on this article has been updated to make clear that 75% of the United States population will see below-freezing temperatures this week. Will this week's temperatures break any of those records? Approximately one quarter of the country will wake up to sub-zero temperatures, and Wednesday might bring about literally the coldest day on record in Chicago, with a projected "high" of 14 below zero. The storm has already set records for cold in Sioux Falls, South Dakota and parts of Canada.
Freezing Tuesday night through Wednesday morning is a concern with the leftover moisture on the roads and temperatures in the low 20s.
Farther north, Ennadai Lake in the Canadian Arctic could see wind chill as low -81 degrees Fahrenheit, NWS reported.