And there has never been more money than in this case.
Bezos, who founded Amazon in his garage in 1994, is considered the richest man in the world with a net worth of $137 billion. They left NY on a road trip to Amazon's eventual headquarters in Seattle, with her driving and him writing up the business plan for what would become the world's largest online retailer.
Bezos also owns the Washington Post newspaper, while the company acquired the Whole Foods supermarket previous year.
Here's a look inside the marriage of Jeff and MacKenzie Bezos. The Bezoses have four children.
"It appears obviously they have significant assets and with a long-term marriage obviously she will be receiving division of assets that I am sure will be significant given both of their circumstances", said Seattle-based family attorney Jennifer Payseno. Ultimately they'll seek a divorce decree stating that the couple's property will be divided according to the agreement.
Amazon shares were up 0.2 per cent in midday trading on Wednesday.
The announcement marked the second time Mr Bezos was in the news this week, after his company Amazon was named the world's most valuable company for a second time, replacing Microsoft at the top spot.
If he signed a prenup, then all those Jeff Bezos assets we discussed are probably off limits in the divorce proceedings.
Jeff, 54, has announced he will divorce his wife MacKenzie. Or even those of other billionaires, such as Donald Trump's tabloid-fodder split with his first wife Ivana in the early 1990s, long before he was elected president.
According to Refinitiv Eikon data, MacKenzie does not hold any Amazon shares directly, while Bezos has a 16.1 percent stake worth about $130 billion.
Jeff and MacKenzie Bezos met in NY at D.E. Shaw.
They were engaged for three months before getting married.
At Princeton, where Jeff also attended, she studied under legendary author Toni Morrison, who told Vogue that she was "one of the best students" she ever had. So long as the company is growing and returning profits, he'll probably maintain their confidence, though a settlement could potentially put a dent in such Bezos side projects as the space exploration company Blue Origin.
The company has since expanded into an e-commerce giant.
However, much of the family fortune is bound up in Amazon stock, with Bezos still integral to the running of the company.