The agency did not disclose any details about the victim in reporting the death Monday.
It's the first Fayette County case of West Nile in a human this year.
The health commissioner says the pattern of hot and wet weather this summer led to an increase in mosquito populations and associated viruses.
This week, the NYDOH believes that someone with the West Nile Virus donated blood, without knowing they ahd the virus.
"Langlade County residents should be aware of West Nile virus and take some simple steps to protect themselves", Thiede said. There have been no deaths from West Nile in 2018. The fever is less serious, and people typically recover on their own. Fewer than one percent develop severe neuro-invasive disease.
Limit outdoor activity from dusk to dawn when mosquitoes are most active.
Apply insect repellents that contain DEET, or other EPA approved product to exposed skin or clothing, and always following the manufacturer's directions for use.
Anyone with symptoms that cause concern should contact his or her health care provider, especially if the symptoms are severe, such as confusion, fever with a stiff neck or muscle weakness or seizures.
Wear long sleeves and trousers during dusk and dawn.
Make sure all windows and doors have screens, and that all screens are in good fix. "Be aware of standing water and come to the health department to get some free dunks to stop mosquitoes at the breeding source".
People 50 years of age and older and individuals with diabetes or hypertension have a higher chance of getting sick, and are more likely to develop complications. The agency tracks certain cases of West Nile and other illnesses spread by mosquitoes with an online map at gis.dhec.sc.gov/mosquitoborne/.