Painkiller linked to increased risk of heart problems

Share

'Considering its cardiovascular and gastrointestinal risks, however, there is little justification to initiate diclofenac treatment before other traditional NSAIDs, ' they said in a statement.

A study published in the British Journal of Clinical Pharmacology focusing on 57,000 people residing in Taiwan also found that taking painkillers such as ibuprofen and naproxen could be linked to having an irregular heartbeat. According to Daily Mail, many parts of the world - including the United Kingdom - have banned diclofenac as an over-the-counter medication because of its adverse effects on the cardiovascular system.

But its cardiovascular risks compared with those of other traditional NSAIDs have never been examined in large randomized controlled trials, and current concerns about these risks make such trials unethical to conduct.

Diclofenac is a medicine that belongs to the category of non-steroidal anti-inflammatory drugs (NSAID) and is used to treat pain and inflammation in many countries of the world (Greece is available only from pharmacies and is not prescribed).

Dr Schmidt and colleagues took a different approach by analysing national registry data for more than 6.3 million middle aged adults in Denmark.

More clear warnings should be given about the risks of diclofenac, say researchers who found a higher risk of heart attack and stroke associated with its use.

Diclofenac is a component which is frequently found in painkillers which are usually used to alleviate back pain, arthritis, and sciatica.

"Treatment of pain and inflammation with NSAIDs may be of value to some patients to improve their quality of life despite possible side effects". Compared with taking paracetamol or ibuprofen, taking diclofenac raised cardiovascular risk by 20 percent.

"After taking account of potentially influential factors, starting diclofenac during the study period was associated with an increased rate of major adverse cardiovascular events within 30 days compared with starting other traditional NSAIDs (ibuprofen or naproxen) or starting paracetamol".

"While NSAID use previously was considered risk-neutral in short treatment periods and low doses, the risks were apparent even within 30 days and also for low doses of diclofenac".

However, while the relative risk increased, the absolute one remained low for the individual patient.

The study also relies on observational data, so it can't directly prove that diclofenac is causing problems. The problems included cardiac arrhythmia, heart failure, ischemic stroke, stroke, premature death of cardiovascular disease and gastrointestinal haemorrhage.

It's always important to discuss medication and the potential risks it will have on your health with a GP or health professional.

Share

Advertisement

Related Posts

Launch of new global estimates on levels of physical activity in adults
As a next step the researchers would work on assessing the levels of activities among the children and youth. In 2001, there were only 31% people that exercised less compared to 37% in 2016.

Leroy Sane leaves Germany squad for "private reasons" after talks with Low
Coach Joachim Low announced his final 23-man list and the Premier League's PFA Young Player of the Year was clearly missing from the team.

India's top court to rule on decriminalizing gay sex
"No one can escape from their individuality", Chief Justice Dipak Misra said , reading from the court's judgment . Gay sex has always been taboo in conservative India - particularly in rural areas where homophobia is widespread.

Mercury rally to edge Seattle, forcing Game 5 in WNBA semifinals
The 6-4 Bonner scored 10 points in Phoenix's 21-5 run and drove again with the game tied at 84 and less than 30 seconds remaining. In the final game of the season last night the Mercury were led by five time All Star Brittney Griner with 21 points 9 rebounds.

Pakistan army chief provokes India, says people of Kashmir fighting bravely
The PM also said that his government wants a foreign policy which will be in the best interest of Pakistan. Bajwa reaffirmed Islamabad's support for "self-determination" in J&K, according to PTI news agency.

Nishikori bests Cilic in US Open rematch, moves to semis
Changing a lot of T-shirts, shorts", said Djokovic. "I was just trying to hang in there and try to find a way to win the match". Suarez celebrated her 30th birthday with a victory over five-time Grand Slam victor Maria Sharapova on Monday.

BMW with Intelligent Personal Assistant; a dream vehicle with smart features
The assistant will also explain how the car's various features work, operating kind of like a verbal user manual. Vehicles will need to be equipped with iDrive 7.0 as part of the Live Cockpit Professional option.

Serena or Osaka? We hit the NY streets to ask fans
They have played once before, earlier this year in Miami, with Osaka besting Serena in straight sets. For Serena Williams , there was no "wait until next year" during the last U.S.

Elon Musk smoking weed is now a meme
The comedian offered the 47-year-old billionaire a marijuana and tobacco cigarette, which are legal in the state of California. He had long argued that AI would be humanity's undoing, with sentient software treating people, at best, like house cats.

China offers tax breaks to some exporters hit by Trump tariffs
The world's two largest economies have already applied tariffs to $50 billion of each other's goods. "That changes the equation". The last effort at a negotiated solution came in late August with meetings between low-level officials , but nothing came of it.

© 2015 ExpressNewsline. All Rights reserved.