Fox has lost a playoff to Scotland's Russell Knox at the Irish Open, missing an eight-foot putt to win the title and then having to watch on as Knox sunk two miraculous putts - the first to force a playoff, and the second to win it.
And when the players returned to the 18th for a sudden-death play-off the situation was remarkably repeated, Knox holing from an nearly identical place for birdie before Fox saw his attempt catch the edge of the hole and spin out.
It was then left to Knox and he delivered in the final holes to set the mark at -14, which was equalled by Ryan Fox, but in the play-off the Scot proved himself with that repeat 40 foot putt.
Campillo finished the first nine on -6 - with Van Rooyen bogeying on 11th to leave the lead at two strokes.
"The putts have been going in these last couple of weeks and I just had a great feeling on the greens and I wasn't really aiming but just reacting to the line of the putt", said Knox.
Fox passed him out with a birdie on 17 to go onto the final hole on -14.
McIlroy will spend several days in London at the start of this week before stepping up his preparation for Carnoustie, where he made his Open debut as an 18-year-old and won the silver medal for leading amateur. "Fortunately I've done it before, so I knew I could do it".
Englishman Andy Sullivan and South African Zander Lombard finished joint sixth to claim Open places.
Van Rooyen had birdied the fourth to move to 15 under but his three bogeys in four holes from the sixth gave hope to the chasing pack.
"It's always nice to play links golf in the run up to an Open and I love the challenge of it".
McIlroy struggled with his putting during the first two rounds but was pleased to see his fortunes improve of the greens on his way to a tied-28th finish.
Fox played some brilliant golf over the 72 holes at Ballyliffin after taking the outright lead in day one and being in the mix all week. Kraft, Snedeker, Kokrak and Austin Cook earned spots in The Open at Carnoustie.
"But right now, I'm going to enjoy this victory and this tournament". I feel like I nearly over-prepared for Shinnecock.
"He also sent me a couple of videos of my body language after all the missed putts this week", laughed the four-time major victor.