One official cautioned, however, that United States intelligence assessments indicate Assad still has chemical weapons in Syria. The Russian vetoes have been one of the main irritants in strained relations between Washington and Moscow, with Western diplomats accusing Russia of trying to protect the Assad government.
In an early-morning tweet, Mr Trump said the strike was "perfectly carried out", and criticised journalists for taking issue with his choice of words.
Trump's declaration of "mission accomplished" had an awkward historic ring.
"Many were excited there is finally something happening, that the (Syrian President Bashar) Assad regime will see some consequences, but other people were quite anxious about civilian casualties, further destruction of Syria", Khatib said.
But it said skies were clear over Aleppo in the north, Hasakeh in the northeast, and Latakia and Tartus along the western coast, where key Syrian and Russian military installations are located. There were no immediate reports of casualties with Damascus's allies saying the buildings hit had been evacuated in advance.
At the Security Council meeting in New York, Russian ambassador Vassily Nebenzia said that Russian and Syrian forces are attacking terrorists, not civilians, and that overnight attack by the USA and its European allies had worsened an "already catastrophic humanitarian situation". "It is a common industrial chemical", said Daryl Kimball at the Washington-based Arms Control Association, who favours broad action to deter use of chemical weapons, including chlorine. French President Emmanuel Macron said the strikes had been limited so far to Syria's chemical weapons facilities. Russian envoy Vassily Nebenzia called for a vote during the meeting on the measure that condemns the "aggression" against Syria and demanded that the allies refrain from any further military strikes.
USA ambassador Nikki Haley warned her United Nations counterparts that although the mission was designed as a one-off, that did not preclude further action against Assad.
GETTYTyphoon aircraft lands at the base in Akrotiri following the strikes in Syria
"When our president draws a red line, our president enforces the red line", Haley stressed. All three participants insisted the strikes were not aimed at toppling Syrian President Bashar al-Assad or intervening in the conflict. China too opposed the strikes.
Saeed Saeed, head of the Institution for the Development of Pharmaceutical and Chemical Industries, said the center was previously used by the Organization for the Prohibition of Chemical Weapons (OPCW) but now works on pharmaceutical products.
- Theresa May told a press conference in London that joining the bombing campaign with the United States and France was the "right thing for us to do" in the wake of the "harrowing" assault on Douma a week ago.
UN Secretary-General Antonio Guterres urged restraint and asked states to avoid any escalation.
The allies also acted because of concerns that Russian and Syrian forces may already have tried to clean up important evidence in Douma, where more than 40 people died in last weekend's attack, the officials said.