With a home game against Burnley also to play before the worldwide break, Pellegrino's Southampton have an ideal opportunity to move up the standings ahead of the two-week pause on domestic action.
Hughton's side failed to deliver a quick response and only threatened Southampton's goal for the first time in the 19th minute when Davy Propper tamely headed Anthony Knockaert's cross into the arms of Fraser Forster.
One of the key factors in Brighton's turnaround has been their impressive performances when playing at Amex Stadium.
Fellow midfielder Beram Kayal and forward Sam Baldock could be included in the matchday squad for the first time this season after their recoveries from a broken leg and calf surgery respectively.
Like their hosts this weekend, Southampton will also be entering the contest coming off the back of a win last weekend.
The lack of a clinical edge invited the Saints back into the fold as Sofiane Boufal and Dusan Tadic linked up in the penalty box in the 35th minute, with the Serbian's shot taking a small deflection which steered the ball just wide of the left upright.
Steven Davis had given Southampton an early lead, but the visitors were pegged back after the interval and missed the chance to climb up to seventh in the Premier League. Mauricio Pellegrino's side have in fact been performing better when the Saint's are away from St. Mary's, Southampton have already picked up five wins away from home this year, one more than their tally at home. The newly promoted side from the south of England have shown to the world that they can compete in the English Premier League and they will also be very desperate to get the three points in this game.
Sunday's showdown on the south coast between Brighton and Hove Albion and Southampton promises to be a captivating contest. Irish global Shane Long enters Sunday's game without scoring a single goal in 27 appearances in all competitions, Southampton will be reliant on Manolo Gabbiadini to lead the attack, the Italian forward has two goals in his last two games. Full-back Jeremy Pied is still in rehab following a groin injury.
If you're a fan of goals, then maybe this isn't the game for you.
- Glenn Murray has scored as many Premier League goals in his last two appearances (three) as he did in his previous 28 PL apps combined.