Makhosi Khoza has announced her resignation from the ANC.
"Despite what is happening to me and to the ANC, I remain hopeful about the future of the country".
Addressing the media on Thursday morning at Liliesleaf Farm, northern Johannesburg, Khoza said the ANC she grew up in had become an "alien and corrupt" party she no longer recognised.
"During the last few months of persecution I had to humble myself in front of my ANC leaders in order to plan my solution". "This new alien ANC is delusional if they think they could".
A party in orange overallsKhoza said that she believes the only way the ANC can root out corruption is if its members are prosecuted and sent to prison. "I'm not leaving the ANC mission".
She said she has chose to leave the party because it is no longer the organisation she knows. "There is a distinction between the ANC values and its leaders".
"This self-correction is not coming".
The backlash followed Khoza's support for a secret vote on the motion of no confidence in President Jacob Zuma.
She was charged by the KwaZulu-Natal ANC for bringing the party into disrepute and for calling for Zuma to step down.
"Yes colonialism oppressed us". Yes apartheid oppressed us.
"I want South Africans to know there are many good comrades within the ANC ... who can not come out in the open for fear of being persecuted".
Khoza has endured weeks of harassment by members of the governing party and was removed as chairperson of the portfolio committee on public service and administration owing to an "irretrievable breakdown of relations between herself and ANC members of the committee". She also thanked several women within the ANC for supporting her, these included Barbara Masekela, Gertrude Shope, Lindiwe Mabuza, Frene Ginwala, Winnie Madikizela-Mandela and Sheila Sisulu.