Judy Foote is announcing her resignation from the federal cabinet and plans to step down as a Liberal MP.
The Canadian cabinet minister in charge of defense procurement quit on Thursday for personal reasons, leaving her successor to tackle a troubled-plagued effort to acquire new fighter jets.
"What the BRCA2 gene means is that you are susceptible to any number of cancers and when it hits your children, it's a totally different ball game", an emotional Foote told a news conference in St. John's, surrounded by her husband, her children and four grandchildren.
Foote's portfolio has been handled on an interim basis by Natural Resources Minister Jim Carr.
A year ago she unveiled plans to buy 18 Boeing Corp Super Hornets as a stop-gap measure while Ottawa prepares an open competition for new jets.
Insiders say Trudeau may also appoint a new female MP to cabinet in order to retain gender parity among his ministers.
Foote had overseen the government's protracted bid to replace its veteran fleet of fighter jets, which is now in some disarray.
Since federal workers had their files moved to Phoenix last spring, tens of thousands of public servants, retirees and employees on leave have reported problems with their pay, with some being overpaid, some paid too little and some not at all.
Foote was first elected to the House of Commons in 2008 and was re-elected in 2011 and 2015 for the region of Bonavista-Burin-Trinity.
Foote began her political career serving as a communications director with former NL Premier Clyde Wells back in the early 90s.
She won the last election with almost 82 per cent of the vote, the highest percentage of any candidate in the country.