It's important to know, HPV is not cancer, but it is related to a lot of cancers.
At least 40 women will die from cervical cancer as a result of the dramatic fall past year in the number of girls taking up a life-saving vaccine in secondary schools, the Irish Cancer Society has said.
Casey Daniel, cancer prevention researcher at USA Mitchell Cancer Institute, stopped by our studio to explain why doctors recommend the vaccinations.
About 90 women will die from cervical cancer and those who survive will need intensive treatment such as surgery, radiotherapy and chemotherapy.
"We have always looked for a cure for cancer and everyone talks about, 'when will we get the cure, '" he said.
The vaccine protects against the main types of HPV virus and reduces the risk of developing cervical cancer and genital warts but does not remove the need for cervical smear tests.
The study was carried out by the HSE Department of Public Health, the National Immunisation Office and the Health Protection Surveillance Centre to determine the association between HPV vaccine uptake for the academic year 2012/2014, before recent anti-HPV vaccine publicity, by school and school characteristics, such as socioeconomic disadvantage and religious ethos.
Donal Buggy, Head of Services and Advocacy at the Irish Cancer Society, said: "When it comes to the HPV vaccine, the jury is in - the vaccine is safe and saves lives".
They're being encouraged to ensure that their girls get the free life-saving vaccine.
She asked parents making the decision about vaccinating their daughters to try to "press the fast-forward button" and to map out what was going to happen to them as 25 year olds.
In November 2015, the European Medicines Agency reported no link between chronic fatigue-like syndromes and the HPV vaccine.
"This is unequivocally a safe vaccine", she said.
New figures from the Irish medical journal also show that girls in disadvantaged areas are least likely to get the vaccine; one of the key areas the campaign will focus on will be bringing facts to marginalised areas. The Centers for Disease Control is recommending that boys and girls, starting at 9-years-old, get the HVP vaccine.