For 70-year-old Harrington it was her 10th Festival victor and added Gold Cup success to the Champion Hurdle and the Queen Mother Champion Chase while for Power it comes 10 years after he won the Grand National on Silver Birch.
The first female jockey in 33 years to race in the Cheltenham Gold Cup has told ITV News "she's not troubled" by being the only girl.
Coinciding with St Patrick's day people have turned out in their droves to watch a day of racing that features one of the most prestigious races of the year.
"This is quite unbelievable", exclaimed former three-day eventer Harrington, the most successful female trainer in the history of the Cheltenham Festival, whose previous stable stars include Champion Hurdle victor Jezki (Ire) (Milan ) and Champion Chaser Moscow Flyer (Ire) (Moscow Society).
"It hasn't really sunk in yet".
"I can't believe it, I've got to get a Classic now (on the Flat)!" "I am about to wake up and it hasn't happened".
"It is the jewel in the crown", she said.
Standing in the winner's enclosure afterwards, after saddling her tenth Festival victor, Harrington was virtually speechless. He invented a machine to do this and made millions from it. He won the three-mile Irish Gold Cup and now the Cheltenham prize over three and a quarter.
Crowned the Queen of Cheltenham, it was a first runner in the Gold Cup for trainer Jessica Harrington.
Both were feeling their way with a horse who had only arrived in Harrington's Moone, Co Kildare yard in the autumn having been moved from Henry De Bromhead's yard by Yorkshire owner, Alan Potts.
"I feel very sorry".
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Two weeks earlier, Djakadam tasted victory in the John Durkan Memorial Punchestown Chase.
I think Augusta Kate was going to beat Death Duty at Naas before falling at the last, Ruby hadn't gone for his stick while Jack Kennedy was at work when she went down and we have a good chance of turning the tables in the Albert Bartlett (2.50). "At least we'd have a Gold Cup victor", he said.
I was 25 when I won the Grand National on Silver Birch and I thought I could win everything after that.
He was sidelined for a couple of weeks at the end of January with a ruptured disc in his back and wore protective goggles until recently for an eye injury he sustained a year ago.
Dual Grand National and Gold Cup-winning Jenny Pitman is no wallflower. "That sounded sweet", he said. There are seven races across the day, with all eyes on the main event - the Cheltenham Gold Cup. Henrietta Knight, who sent out Best Mate to three consecutive wins in the Gold Cup, has an inner steel that belies her courteousy. But after making a costly jumping error at the second-to-last fence. he faded to finish fourth.
It followed their Coral Cup victory with Supasundae on Wednesday.
Master Blueyes can be a good each-way punt in the opening Triumph Hurdle but Defi De Sueil looks the best horse in the race and should give JP McManus another victor here this week. He may go to Aintree for the Bowl as he ran well there previous year, depending on how he comes out of his race.
"It's an unbelievable feeling", said Frost after triumphing aboard the Paul Nicholls-trained runner. Between them, Ireland claimed six of the seven races.
"It is great to do".
"We are all trainers", she said, dismissively.
From the beginning on Tuesday - with Elliott's Laiback - to the end on Friday, the Irish were in the ascendancy. "I've been watching and listening for as long as I can remember".